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Probability Models for DNA Sequence Evolution Hardcover Rick Durr
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eBay item number:315245366784
Item specifics
- Condition
- Good
- Seller Notes
- Features
- EX-LIBRARY
- Book Title
- Probability Models for DNA Sequence Evolution Hardcover Rick Durr
- ISBN
- 9780387954356
- Series
- Probability and Its Applications Ser.
- Publication Year
- 2002
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Publication Name
- Probability Models for D N A Sequence Evolution
- Item Length
- 9.3in
- Publisher
- Springer
- Item Width
- 6.1in
- Item Weight
- 16.9 Oz
- Number of Pages
- VIII, 240 Pages
About this product
Product Information
As a starting point to this volume, the authors address the fundamental question What underlying forces are responsible for the observed patterns of variability, given a collection of DNA sequences? In approaching this question they introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model and the infinite sites model. They then discuss the complications that come from nonconstant population size, recombination, population subdivision and three forms of natural selection: directional selection, balancing selection and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from neutral evolution.
Product Identifiers
Publisher
Springer
ISBN-10
038795435x
ISBN-13
9780387954356
eBay Product ID (ePID)
24038308654
Product Key Features
Publication Name
Probability Models for D N A Sequence Evolution
Format
Hardcover
Language
English
Series
Probability and Its Applications Ser.
Publication Year
2002
Type
Textbook
Number of Pages
VIII, 240 Pages
Dimensions
Item Length
9.3in
Item Width
6.1in
Item Weight
16.9 Oz
Additional Product Features
Lc Classification Number
Qh438.4.S73d87 2002
Reviews
From the reviews: This book serves as an introduction to, and a compilation of, results in the new and growing field of probability theory for DNA evolution. The author is a probabilist, but he has made an effort to appeal to biologists and mathematicians alike. Biologists will find in this book those methods used for studying DNA variability that go beyond straightforward applications of statistics and require genuine mathematical insight into the underlying mechanisms. The example data are real and the driving motivation is to understand these truthfully. Mathematicians will find in this book not an attempt to develop some abstract theory, but rather a kaleidoscopic collection of ideas and methods invented to attack a common problem. The emphasis is on catching the main ideas in down-to-earth calculations; continuum models and more sophisticated methods from analysis are avoided. The book starts with the Wright-Fisher model for neutral selection in a constant population, and then builds and varies on this in Chapters 1--3 by adding the effects of mutation, recombination, selection, nonconstant population sizes and spatial structure. Chapter 4 is devoted to statistical tests for detecting departures from the neutral model and Chapter 5 discusses the large-scale structure of the DNA such as the size and number of chromosomes, inversions, translocations and duplications. This book will serve as a useful guide to this new and exciting field and an inspiration even for the more experienced readers.--Mathematical Reviews "With numerous interspersed example datasets from the primary literature, this book offers a brief introduction to models of both long-term and short-term DNA sequence evolution, with emphasis on the lattera? Diverse audiences will find much of the value in this concise book. The authora's rigor and ability to embed material in a broader mathematical context will appeal to quantitative readers with little background in biologya? The booka's strength is in its mathematical content, which revives almost-forgotten theorems, includes new proofs, and is thorough but not overwhelmingly detailed or overburdened with notation."Journal of the American Statistical Association, June 2004 "Stochastic modelling of genetic sequences and their evolution continues to be one of the hottest areas of research in applied probability even today. This book is a useful and interesting addition to a large number of similar texts in this area. ... it is surely a reliable introductory text for beginners taking interest in the subject." (Probal Chaudhuri, Sankhya: The Indian Journal of Statistics, Vol. 65 (4), 2003) "This is the first book covering the mathematical theory of molecular evolution developed during the last two decades. a? A particularly pleasing feature of this text is that most important concepts and results are immediately applied to real data, thus providing many illuminating examples. This book can be highly recommended to students and researchers in applied probability and mathematical biology, especially to those interested in genetics, evolution, or bioinformatics." (R.B'rger, Monatshefte f'r Mathematik, Vol. 143 (1), 2004) "The author did an admirable job in providing a concise and up-to-date summary of modern molecular population genetics. The details of derivations are often given, allowing the reader to follow the theory. a? Overall, I found the book great fun to read. I recommend it to population geneticists who are interested in a concise modern summary of analytical results in the field, and to mathematicians who would like to work in this exciting area of research." (Z Yang, Heredity, Vol. 92, 2004) "This book serves as an introduction to, and a compilation of, results in the new and growing field of probability theory for DNA evolution. The author is a probabilist, but he has made an effort to appeal to biologists and mathemati
Copyright Date
2002
Target Audience
Scholarly & Professional
Topic
Biostatistics, Probability & Statistics / General, Life Sciences / Genetics & Genomics, Life Sciences / Biology, Applied
Lccn
2002-016001
Dewey Decimal
572.8/38/0727
Dewey Edition
21
Illustrated
Yes
Genre
Science, Mathematics, Medical
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eBay item number:315245366784
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n***- (7)- Feedback left by buyer.
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Very fast shipping. Somewhat disappointed that the edition received is not the edition pictured in the listing. The listing itself clarifies this though, so that’s mostly my fault for not reading closer. Still happy with the purchase and service.
0***0 (30)- Feedback left by buyer.
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Llegó en buen estado y bien protegido pero la portada no concuerda con la que se ve en la imagen.
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Arrived in described condition! Packed in a stuff paper mailer.
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