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Probability Models for DNA Sequence Evolution (Probability and Its Applications
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eBay item number:394964223344
Item specifics
- Condition
- Book Title
- Probability Models for DNA Sequence Evolution (Probability and It
- ISBN
- 9780387954356
- Publication Year
- 2002
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Publication Name
- Probability Models for Dna Sequence Evolution
- Item Height
- 234mm
- Publisher
- Springer-Verlag New York Inc.
- Item Width
- 156mm
- Subject
- Biology, Mathematics
- Item Weight
- 544g
- Number of Pages
- 248 Pages
About this product
Product Information
Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability? To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. We study the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from neutral evolution. The final chapter studies the evolution of whole genomes by chromosomal inversions, reciprocal translocations, and genome duplication. Throughout the book, the theory is developed in close connection with data from more than 60 experimental studies from the biology literature that illustrate the use of these results. This book is written for mathematicians and for biologists alike. We assume no previous knowledge of concepts from biology and only a basic knowledge of probability: a one semester undergraduate course and some familiarity with Markov chains and Poisson processes. Rick Durrett received his Ph.D. in operations research from Stanford University in 1976. He taught in the UCLA mathematics department before coming to Cornell in 1985. He is the author of six books and 125 research papers, and is the academic father of more than 30 Ph.D. students. His current interests are the use of probability models in genetics and ecology, and decreasing the mean and variance of his golf.
Product Identifiers
Publisher
Springer-Verlag New York Inc.
ISBN-13
9780387954356
eBay Product ID (ePID)
89993794
Product Key Features
Publication Name
Probability Models for Dna Sequence Evolution
Format
Hardcover
Language
English
Subject
Biology, Mathematics
Publication Year
2002
Type
Textbook
Number of Pages
248 Pages
Dimensions
Item Height
234mm
Item Width
156mm
Item Weight
544g
Additional Product Features
Series Title
Probability and Its Applications
Country/Region of Manufacture
United States
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- GB 858 5123 06
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eBay item number:394964223344
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